Medicis Reports Record Fourth Quarter and Fiscal Year Financial Results

SCOTTSDALE, Ariz.--Aug. 23, 2000--Medicis Pharmaceutical Corporation (NYSE:MRX) today announced fiscal 2000 net income of $43.0 million, or $1.41 per diluted share, on net revenues of $139.1 million, versus fiscal 1999 comparative net income of $32.9 million, or $1.12 per diluted share, on net revenues of $97.5 million. Fiscal 1999 results exclude revenue and income associated with product divestitures and special charges. Absent revenues associated with the divested brands, fiscal 2000 net revenue increased approximately 41% as compared to fiscal 1999.

The Company also reported fourth-quarter fiscal 2000 net income of $11.8 million, or $0.38 per diluted share, on net revenues of $39.0 million, versus fourth-quarter fiscal 1999 comparative net income of $10.2 million, or $0.35 per diluted share, on net revenues of $32.1 million. Fourth-quarter fiscal 1999 results exclude revenue and income associated with product divestitures. Absent revenues associated with the divested brands, fourth-quarter fiscal 2000 net revenues increased approximately 25% as compared to fourth-quarter fiscal 1999.

The strong fiscal year and fourth quarter operating results are attributable primarily to the growth of the Company's core prescription brands. During fiscal 2000, prescription volume growth in the Company's core brands, DYNACIN(R), LUSTRA(R), LOPROX(R) and TRIAZ(R) was nearly 40 percent. Additionally, during the fiscal year, Medicis introduced three new products from its research and development pipeline, LOPROX(R) Gel, PLEXION(TM) and TRIAZ(R) 3%.

Fiscal 1999 revenues included $19.3 million of sales from products divested. Absent management's estimate of the net income associated with the divested products, the tax-effected gain on the divestiture of such brands and the tax-effected charge for in-process research and development associated with the acquisition of LOPROX(R), TOPICORT(R) and A/T/S(R), net income for fiscal 1999 was approximately $32.9 million, or $1.12 per diluted share. Inclusive of all special adjustments, Medicis reported fiscal 1999 net revenues of $116.9 million, with net income of $41.4 million, or $1.41 per diluted share.

"We are pleased to announce another record quarter and fiscal year financial results," said Jonah Shacknai, Chairman and Chief Executive Officer of Medicis. "In fiscal 2000, we again executed our four-part growth strategy. Our sales and marketing organization increased prescription growth of our core prescription brands nearly forty percent, while our research and development team launched three new products from our robust pipeline. We enter a new fiscal year with great enthusiasm for our recently announced collaboration with Corixa on an exciting and novel psoriasis treatment and reaffirm our commitment to become the nation's premier dermatology concern."

Medicis is the leading independent pharmaceutical company in the United States focusing primarily on the treatment of dermatological conditions. Medicis develops and markets leading products for major segments within dermatology including acne, fungal infections, psoriasis, eczema, rosacea, seborrheic dermatitis, head lice and cosmesis (improvement in the texture and appearance of skin). Primary products include the prescription brands DYNACIN(R) (minocycline HCl), TRIAZ(R) (benzoyl peroxide), LUSTRA(R) (hydroquinone), LOPROX(R) (ciclopirox), OVIDE(R) (malathion), PLEXION(TM) (sodium sulfacetamide/sulfur), LIDEX(R) (fluocinonide), SYNALAR(R) (fluocinolone acetonide), TOPICORT(R) (desoximetasone), NOVACET(R) (sodium sulfacetamide/sulfur) and A/T/S(R) (erythromycin); the over-the-counter brand ESOTERICA(R); and BUPHENYL(TM) (sodium phenylbutyrate), a prescription product indicated in the treatment of Urea Cycle Disorder.

Except for historical information, this news release contains certain forward-looking statements that involve risks and uncertainties which may cause actual results to differ materially from the statements made, including the Company's dependence on sales of key products, uncertainty of future financial results and fluctuations in operating results, dependence on the Company's acquisition strategy, new product introductions and other risks described from time to time in the Company's SEC filings. These forward-looking statements represent the judgment of the Company, as of the date of this release, and Medicis disclaims any intent or obligation to update these forward-looking statements.

NOTE: Full prescribing information for any Medicis prescription product is available by contacting the Company.



                  Medicis Pharmaceutical Corporation
                 (in thousands, except per share data)
                   Summary Statements of Operations
                   --------------------------------


                          Three Months Ended        Year Ended
                                June 30,              June 30,
                         --------------------  --------------------
                             2000       1999       2000       1999
                         --------------------  --------------------
Revenues                 $  39,027  $  33,892  $ 139,099  $ 116,871
Cost of sales                7,364      6,587     25,911     21,635
                         ---------  ---------  ---------  ---------
  Gross profit              31,663     27,305    113,188     95,236
Operating expenses:
  Selling, general
   and administrative       14,008     11,030     45,404     38,219
  Research and
   development               1,465      1,482      4,903      3,396
  Depreciation and
   amortization              1,898      1,931      7,375      5,810
                         ---------  ---------  ---------  ---------
    Total operating
     expenses               17,371     14,443     57,682     47,425
                         ---------  ---------  ---------  ---------
  In-process research
   and development            --         --         --        9,500
                         ---------  ---------  ---------  ---------
Operating income            14,292     12,862     55,506     38,311
Interest income, net         3,637      2,055     11,875      9,678
Gain on sale of assets        --       10,515       --       17,650
Income tax expense          (6,119)    (9,240)   (24,387)   (24,202)
                         ---------  ---------  ---------  ---------
  Net income             $  11,810  $  16,192  $  42,994  $  41,437
                         =========  =========  =========  =========
Basic net income per
 common share            $    0.40  $    0.57  $    1.48  $    1.46
                         =========  =========  =========  =========
Diluted net income
 per common share        $    0.38  $    0.55  $    1.41  $    1.41
                         =========  =========  =========  =========
Shares used in basic
 net income per
 common share               29,375     28,645     29,029     28,414
Shares used in
 diluted net income
 per common share           31,079     29,343     30,499     29,462

----------------------------------------------------------------------
Absent tax-effected special adjustments for in-process R&D,
 management's estimate of net income associated with divested products
 and gain on sale of divested products:

  Net income              $ 11,810   $ 10,165   $ 42,994   $ 32,893
                          ========   ========   ========   ========
  Basic net income per
   common share           $   0.40   $   0.35   $   1.48   $   1.16
                          ========   ========   ========   ========
  Diluted net income
   per common share       $   0.38   $   0.35   $   1.41   $   1.12
                          ========   ========   =========  ========
----------------------------------------------------------------------

                            Balance Sheets
                            --------------
                                             At June 30, At June 30,
                                                 2000       1999
                                             ----------- -----------
Assets
  Cash and short-term investments              $285,737   $237,304
  Other current assets                           65,551     98,288
                                               --------   --------
    Total current assets                        351,288    335,592
  Property and equipment, net                     1,759      1,705
  Intangible assets, net                        141,182    128,976
  Other assets                                    1,110      1,237
                                               --------   --------
    Total assets                               $495,339   $467,510
                                               ========   ========

Liabilities and stockholders' equity
  Current liabilities                          $ 38,987   $ 56,980
  Deferred tax liabilities                        4,000      1,935
  Other non-current liabilities                    --          130
  Long-term obligations                          14,913     34,717
  Stockholders' equity                          437,439    373,748
                                               --------   --------
    Total liabilities and stockholders'
     equity                                    $495,339   $467,510
                                               ========   ========

Working capital                                $312,301   $278,612
                                               ========   ========
Contacts:
Medicis Pharmaceutical Corporation, Scottsdale
Libby Ivy, 602/808-3854
www.medicis.com


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